Introduction

MutCompute.com is an online platform focused on the computation and design of protein mutations, primarily serving researchers in the fields of bioinformatics, structural biology and protein engineering. Its core function is to help scientists better understand the behavior of proteins and design new proteins with specific functions by computationally simulating and predicting the effects of protein mutations on their structure and function. Proteins are important molecules for life activities, and their functions are determined by their three-dimensional structures. Scientists often alter the amino acid sequence of proteins (i.e., mutation) to study their function or design new proteins. However, experimental methods are time-consuming and costly, so computational tools have become an important aid. mutCompute was created for this purpose, and it helps researchers to quickly screen potential mutation solutions by predicting the effects of mutations on proteins through algorithms and models.

MutCompute is based on molecular dynamics simulations, machine learning and bioinformatics algorithms. It predicts the effects of mutations by analyzing the physicochemical properties of proteins (e.g. hydrogen bonding, hydrophobic interactions, etc.). Machine learning models are then trained with a large amount of known protein mutation data to improve the accuracy of the predictions.The MutCompute platform is primarily aimed at researchers, including biologists, chemists and drug developers. For example, in drug development, scientists can use the platform to predict the effects of mutations on drug target proteins to optimize drug design.

Website Registration

The site is registered at https://mutcompute.com/register As shown below.

MutCompute is for academic use only. User must provide an academic email address for valid registration.

MutCompute is for academic use only. Users must provide an academic email address for valid registration, after our testing edu.cn does not meet the requirements, even fudan.edu.cn famous schools do not meet the requirements, it will prompt the following picture. Please be consistent with the requested format.

We use a foreign American university edu email address to register, and will be prompted directly with a Status Sent email confirmation to send a confirmation link to activate your account.

Status,Sent email confirmation link,token,IkJydW5

我们打开edu邮箱提示收到no-reply@mutcompute.com发送的标题为:"MutCompute Email Confirmation "Confirmation Mail:

You are attempting to create an account to access mutCompute.Please click the link below to confirm your email address and activate your account:http:// mutcompute.com/api/email_confirmation/Ik

You are trying to create an account to access mutCompute. Please click on the link below to confirm your email address and activate your account.